Work

Regulating Adipogenesis

Year: 1997

Type: review

Abstract: The raison d'etre of the adipocyte is to store energy (in the form of triacylglycerol) for use during periods of caloric insufficiency. Adipocytes first appear late in fetal development preparatory to postnatal life when a substantial energy reserve is needed to survive periods of fasting. Considerable progress has been made during the past few years in our understanding of the adipocyte differentiation program. This review will focus on the roles of the CAAT/enhancer binding protein (C/EBP)1 and peroxisome proliferator-activated receptor (PPAR) families of transcription factors in the differentiation program.

Source: Journal of Biological Chemistry

DOI: 10.1074/jbc.272.9.5367

Authors: Susanne Mandrup, M.Daniel Lane

Institutions: Johns Hopkins University, Johns Hopkins Medicine

Language: English

Topic: Peroxisome Proliferator-Activated Receptors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,430