Year: 2007
Type: letter
Abstract: variables was prospectively planned in a phase II trial, 5 and their prognostic value has been confirmed in that trial.In fact, the variables included in the IELSG score can be routinely collected for PCNSL patients if prospectively planned.The score proposed by Abrey et al 1 is simple, but simplicity could be to the detriment of accuracy.Present data show that the use of a disease-specific score, which includes LDH serum level, CSF protein level, and involvement of deep regions of the brain other than age and PS will result in a better risk stratification of PCNSL patients enrolled in prospective trials.The IELSG prognostic score, in fact, follows the model of the International Prognostic Index for aggressive lymphomas, 8 which includes variables related to aggressiveness, extension and site of disease other than age and PS.We hope that a more diffuse use of the IELSG prognostic score could have a similar impact on clinical practice and prospective trials than those eventually demonstrated for the International Prognostic Index.
Source: Journal of Clinical Oncology
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4249030077