Work

Proteolytic Processing of the β-Subunit of the Lysosomal Enzyme, β-Hexosaminidase, in Normal Human Fibroblasts

Year: 1989

Type: article

Abstract: We have characterized the proteolytic processing of the @-subunit of &hexosaminidase by identifying the amino termini of the various forms synthesized in cellfree translation and in cultured human fibroblasts.The procedures used had been developed for similar studies of the a-subunit (Little, L. E.,

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(18)94077-9

Authors: D V K Quon, R L Proia, A V Fowler, J Bleibaum, E F Neufeld

Institutions: National Institutes of Health, University of California, Los Angeles, National Institute of Diabetes and Digestive and Kidney Diseases

Language: English

Topic: Lysosomal Storage Disorders Research

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

Funder: National Institute of Neurological Disorders and Stroke