Year: 2020
Type: other
Abstract: Objective: Previous prospective studies on association of white rice intake with incident diabetes have shown contradictory results but were conducted in single countries and predominantly in Asia. We report on the association of white rice with risk of diabetes in the multinational Prospective Urban Rural Epidemiology (PURE) study. Research design and methods: Data on 132,373 individuals aged 35-70 years, from 21 countries. were analysed. White rice consumption (cooked) was categorised as <150, ≥150 to <300, ≥300 to <450 and ≥450 grams/day, based on 1 cup of cooked rice = 150 grams. The primary outcome was incident diabetes. Hazards ratios were calculated using multivariable Cox frailty model. Results: During a mean follow up period of 9.5 years, 6,129 individuals without baseline diabetes developed incident diabetes. In the overall cohort, higher intake of white rice (≥450g/d compared with <150g/d) was associated with increased risk of diabetes (HR: 1.20; 95% CI: 1.03-1.41 p for trend=0.003). However, the highest risk was seen in South Asia (HR: 1.65; 95% CI: 1.17-2.34, p for trend=0.02), followed by other regions of the world (which included South East Asia, Middle East, South America, North America/Europe and Africa) (HR: 1.41; 95% CI: 1.08-1.85, p for trend =0.01), while in China there was no significant association (HR: 1.05; 95% CI: 0.78-1.41, p for trend = 0.38). Conclusions: Higher consumption of white rice is associated with an increased risk of incident diabetes with the strongest association being observed in South Asia, while in other regions, a modest, non-significant association was seen.
Authors: Balaji Bhavadharini, Viswanathan Mohan, Mahshid Dehghan, Sumathy Rangarajan, Sumathi Swaminathan, Annika Rosengren, Andreas Wielgosz, Alvaro Avezum, Patricio Lopez-Jaramillo, Fernando Lanas, Antonio L Dans, Karen Yeates, Paul Poirier, Jephat Chifamba, Khalid F Alhabib, Noushin Mohammadifard, Katarzyna Zatońska, Rasha Khatib, Mirac Vural Keskinler, Li Wei, Chuangshi Wang, Xiaoyun Liu, Romaina Iqbal, Rita Yusuf, Edelweiss Wentzel-Viljoen, Afzal Hussein Yusufali, Rafael Diaz, NG Kien Keat, PVM Lakshmi, Noorhassim Ismail, Rajeev Gupta, Lia M Palileo-Villanueva, Patrick Sheridan, Andrew Mente, Salim Yusuf
Language: English
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4252898790