Work

Author response: Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells

Year: 2017

Type: peer-review

Abstract: The rapid killing of macrophages by Mycobacterium tuberculosis aggregates, and the subsequent proliferation of the bacteria inside the dead cell, leads to a cell death cascade and explains the coupling of necrosis and pathogen growth observed in active disease.

Source: eLife

DOI: 10.7554/elife.22028.037

Authors: Deeqa Mahamed, Mikael Boulle, Yashica Ganga, Chanelle Mc Arthur, Steven Skroch, Lance Oom, Oana Catinas, Kelly Pillay, Myshnee Naicker, Sanisha Rampersad, Colisile Mathonsi, Jessica Hunter, Emily B Wong, Moosa Suleman, Gopalkrishna Sreejit, Alexander S Pym, Gila Lustig, Alex Sigal

Institutions: University of KwaZulu-Natal, Max Planck Institute for Infection Biology, Massachusetts General Hospital

Language: English

Topic: Tuberculosis Research and Epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500

OpenAlex ID: W4254516741

Cites:

Cited by: 2

Related to: 10