Work

An Immunogenic and Slow-Growing Cryptococcal Strain Induces a Chronic Granulomatous Infection in Murine Lungs

Year: 2022

Type: article

Abstract: Many successful pathogens cause latent infections, remaining dormant within the host for years but retaining the ability to reactivate to cause symptomatic disease. The human opportunistic fungal pathogen Cryptococcus neoformans establishes latent pulmonary infections in immunocompetent individuals upon inhalation from the environment.

Source: Infection and Immunity

DOI: 10.1128/iai.00580-21

Authors: Calla L. Telzrow, Shannon Esher Righi, Natalia Castro-Lopez, Althea Campuzano, Jacob T. Brooks, John M. Carney, Floyd L. Wormley, J. Andrew Alspaugh

Institutions: Duke University, Duke Medical Center, Tulane University, Texas Christian University, The University of Texas at San Antonio, University of North Carolina at Chapel Hill

Language: English

Topic: Fungal Infections and Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: G5306807608, Coordinated Regulation of Virulence Genes in C. neoformans, UTSA RISE Research Training Program

OpenAlex ID: W4280494441

FWCI: 2.344

Cites: 63

Cited by: 18

Related to: 10