Work

CD70 CAR T cells in AML: Form follows function

Year: 2022

Type: article

Abstract: Using a multimodal approach toward developing a new CD70-targeted Chimeric antigen receptor (CAR) T cell in acute myeloid leukemia, Leick et al. 1 report on their synergetic strategy, which incorporates both CAR T cell construct modifications with enhancement of leukemia antigen expression to improve CAR T cell functionality.

Source: Cell Reports Medicine

DOI: 10.1016/j.xcrm.2022.100639

Authors: Justin Mirazee, Nirali N. Shah

Institutions: National Institutes of Health, Johns Hopkins University, National Cancer Institute, Center for Cancer Research

Language: English

Topic: CAR-T cell therapy research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,200