Work

Interpersonal Variability in Gut Microbial Calprotectin Metabolism

Year: 2022

Type: article

Abstract: Ulcerative colitis (UC) and Crohn’s disease (CD) are immune-mediated chronic inflammatory bowel diseases (IBDs) of the gastrointestinal tract. The gold standard for assessing mucosal inflammation is through endoscopy with biopsies, which permits providers to define the severity and distribution of intestinal inflammation visually and histologically. However, endoscopy is impractical as a tool for monitoring patients on a daily or weekly basis. There is a clinical need for reliable noninvasive testing to monitor IBD patients.

Source: Gastro Hep Advances

DOI: 10.1016/j.gastha.2022.05.007

Authors: K. Kamp, N. Li, D.M. Lachance, K. Saad, E. Tolentino, L. Yoo, M.M. Heitkemper, K. Clark-Snustad, S.D. Lee, N. Dey

Institutions: University of Washington, Fred Hutch Cancer Center

Language: English

Topic: Inflammatory Bowel Disease

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,000

Funders: Pfizer, University of Washington, National Institutes of Health, National Institute of Nursing Research, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: The gut microbiota, bile acid-mediated enteric nervous system signaling, and modulation of gastrointestinal motility, Center for Innovation in Sleep Self-Management (CISSM), Interdisciplinary Nurse Scientist Training in Multilevel Approaches: Biology to Society, University of Washington GI Training Grant

OpenAlex ID: W4280561660

FWCI: 0.604

Cites: 8

Cited by: 4

Related to: 10