Work

Stochastic mRNA production by a three-state gene

Year: 2022

Type: preprint

Abstract: We consider a model of mRNA production governed by the dynamics of a gene that exists in three possible states -- inactive, poised and active. The transitions between the adjacent states are controlled by stochastic processes characterized by corresponding on/off rates. mRNA is produced only when the gene is in active state and we also consider mRNA denaturation leading to its death.

Source: arXiv (Cornell University)

DOI: 10.48550/arxiv.2205.09271

Authors: Rubinstein, Boris, Unruh, Jay, Zeitlinger, Julia

Institutions: Stowers Institute for Medical Research, Research Medical Center

Language: English

Topic: Gene Regulatory Network Analysis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W4281257080

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