Severe Hypoglycemia Caused by a Giant Borderline Phyllodes Tumor of the Breast: A Case Report and Literature Review
Year: 2022
Type: article
Study design: Case Report
Abstract: A case of hypoglycemic coma caused by a giant borderline phyllodes tumor of the breast has been described. The patient, a 63-year-old woman, was admitted with recurrent unconsciousness. She had a giant breast tumor with decreased blood glucose, insulin, and C-peptide. The patient's hypoglycemia resolved rapidly after resection of the breast tumor. Pathological examination indicated a borderline phyllodes tumor of the breast, and immunohistochemistry suggested high expression of insulin-like growth factor-2 (IGF-2) in the tumor tissue. A literature review is also included to summarize the clinical characteristics of such patients and to serve as a unique resource for clinical diagnosis and treatment of similar cases.
Source: Frontiers in Endocrinology
Institutions: University of Electronic Science and Technology of China, Chinese Academy of Sciences, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Sichuan University, West China Medical Center of Sichuan University, West China Second University Hospital of Sichuan University
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,950
Awards: G2046063097, G2713490819, G2735878915
OpenAlex ID: W4281558080