Year: 2022
Type: article
Abstract: IL-1β is one of the important IL-1 superfamily cytokines that shows crucial role in the pathogenesis of various inflammatory disorders like osteoarthritis, epidermolysis bullosa, psoriasis and type II diabetes. Dugs with IL-1βinhibitory effect can show promising results in these types of inflammatory disorders. Diacerein and its active metabolite rhein prevent the generation of active IL-1 and are consequently used to treat inflammatory conditions such as osteoarthritis, epidermolysis bullosa, psoriasis, and Type II diabetes.
Authors: Tathagata Roy, Rishta Roy Chowdhury, Payel Chakraborty, Subhendu Dey, Tapan Kumar Chatterjee
Language: English
Subfield: Plant Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4281639874