Work

Discovery of 1,6-Naphthyridin-2(1H)-one Derivatives as Novel, Potent, and Selective FGFR4 Inhibitors for the Treatment of Hepatocellular Carcinoma

Year: 2022

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.1c01977

Authors: Xiaomeng Zhang, Yazhou Wang, Jianfeng Ji, Dongjuan Si, Xueting Bao, Zhuangzhuang Yu, Yueyue Zhu, Liwen Zhao, Wei Li, Jian Liu

Institutions: Nanjing University of Chinese Medicine, Nanjing Sanhome Pharmaceutical Co., Ltd. (China)

Language: English

Topic: Fibroblast Growth Factor Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Natural Science Foundation of Jiangsu Province, Nanjing University of Chinese Medicine

Awards: G1284177061, G190202158, G2470895010, G4795416507

OpenAlex ID: W4281705510

FWCI: 2.531

Cites: 44

Cited by: 36

Related to: 10