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Drug design and DNA structural research inspired by the Neidle laboratory: DNA minor groove binding and transcription factor inhibition by thiophene diamidines

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Year: 2022
Type: article
Source: Bioorganic & Medicinal Chemistry
DOI: 10.1016/j.bmc.2022.116861
Authors: Edwin N. Ogbonna, Ananya Paul, J. Ross Terrell, Ziyuan Fang, Cen Chen, Gregory M.K. Poon, David W Boykin, W. David Wilson
Institution: Georgia State University
Language: English

Topic: DNA and Nucleic Acid Chemistry
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: bronze

Funders: National Science Foundation, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences
Awards: G2676711533, Direct chemical control of the hematopoietic master transcription factor PU.1, Folded state dynamics and hydration in transcriptional regulation, A cellular osmotic pressure sensor, Molecular Design for Specific Recognition of Functional DNA Sequences, G9000137677
OpenAlex ID: W4281734708
FWCI: 0.734
Cites: 66
Cited by: 10
Related to: 10
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