Mapping of SARS-CoV-2 IgM and IgG in gingival crevicular fluid: Antibody dynamics and linkage to severity of COVID-19 in hospital inpatients
Year: 2022
Type: article
Abstract: The use of non-venous analytes has been a priority public health tool for the diagnosis, monitoring and surveillance of a range of pathogens. These methods, primarily based on Dried Blood Spots (DBS) and Gingival Crevicular Fluid (GCF), were first developed in the UK and have been applied to investigate outbreak and transmission events,1,2 to improve the diagnosis of infections in underserved populations3,4 in addition to monitoring infection trends and informing on the impact of interventions.5,6
Source: Journal of Infection
Authors: Samreen Ijaz, Steve Dicks, Keerthana Jegatheesan, Eleanor Parker, Ksenia Katsanovskaja, Elen Vink, Myra O. McClure, J. Shute, Joshua Hope, Nicola Cook, Peter Cherepanov, Lance Turtle, William A. Paxton, Georgios Pollakis, Antonia Ho, Peter J.M. Openshaw, J. Kenneth Baillie, Malcolm G. Semple, Richard S. Tedder
Institutions: UK Health Security Agency, NHS Blood and Transplant, Imperial College London, MRC University of Glasgow Centre for Virus Research, University of Glasgow, Medical Research Council, The Francis Crick Institute, University of Liverpool, Liverpool University Hospitals NHS Foundation Trust, Health Protection Research Unit in Emerging and Zoonotic Infections at University of Liverpool, Roslin Institute, University of Edinburgh, Alder Hey Children's Hospital
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,400
Funders: Wellcome Trust, Francis Crick Institute, UK Research and Innovation, National Institute for Health Research Health Protection Research Unit, Cancer Research UK, National Institute for Health and Care Research, Imperial College London, University of Oxford, Medical Research Council, Biotechnology and Biological Sciences Research Council
Awards: G1204445118, G1680552280, G1757733276, G1962299536, G2404953410, NIHR Senior Investigator Award, G310335178, Understanding the SARS-CoV2 virus and the pathogenesis and transmission of COVID-19., G3159248960, Clinical Characterisation of COVID-19 admitted to hospitals in the United Kingdom, G3678162129, G4388622794, G4689083255, G4772707521, G5208948526, G5449738238, G5787046253, G6091644065, G6206044308, G655254616, G6795691369, G7066232665, Host responses underlying immunity, G7499770399, G7725255074, G8038231773, G868801089, G869621869, In vivo and in situ modelling of endoplasmic reticulum shaping defects on mitochondrial function in hereditary spastic paraplegias, G957827840
OpenAlex ID: W4281741609