Extraskeletal calcifications in a dialysis-dependent teenager: A novel cause of acquired pediatric complete heart block
Year: 2022
Type: article
Abstract: Key Teaching Points•Renal failure may lead to visceral calcium deposition resulting from secondary hyperparathyroidism, hypercalcemia, and hyperphosphatemia. These calcium deposits have been described in a variety of tissues, including the myocardium, coronary arteries, and cardiac valves.•Calcium deposition in the region of the cardiac conduction system, including the location of the atrioventricular node, can lead to complete heart block. This calcium deposition may be due to renal failure or other etiologies such as Paget’s disease, parathyroid gland neoplasms, or atherosclerosis-related calcification.•Calcification of the atrioventricular node is a rare and potentially life-threatening complication of renal failure in both adults and children. Pacemaker implantation may be indicated. •Renal failure may lead to visceral calcium deposition resulting from secondary hyperparathyroidism, hypercalcemia, and hyperphosphatemia. These calcium deposits have been described in a variety of tissues, including the myocardium, coronary arteries, and cardiac valves.•Calcium deposition in the region of the cardiac conduction system, including the location of the atrioventricular node, can lead to complete heart block. This calcium deposition may be due to renal failure or other etiologies such as Paget’s disease, parathyroid gland neoplasms, or atherosclerosis-related calcification.•Calcification of the atrioventricular node is a rare and potentially life-threatening complication of renal failure in both adults and children. Pacemaker implantation may be indicated.
Source: HeartRhythm Case Reports
Institutions: Baylor College of Medicine, Texas Children's Hospital
Language: English
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,050
OpenAlex ID: W4281745255