Work

Cardiolipin Biosynthesis Genes Are Not Required for Salmonella enterica Serovar Typhimurium Pathogenesis in C57BL/6J Mice

Year: 2022

Type: article

Abstract: Salmonella enterica serovar Typhimurium is a pathogenic Gram-negative bacterium that regulates the cardiolipin (CL) and lipopolysaccharide (LPS) composition of the outer membrane (OM) during infection. Mitochondrial CL molecules activate the inflammasome and its effector caspase-1, which initiates an inflammatory process called pyroptosis.

Source: Microbiology Spectrum

DOI: 10.1128/spectrum.02617-21

Authors: Melina B. Cian, Joshua A. Mettlach, Aaron E. Zahn, Nicole P. Giordano, Keaton E. Minor, Michael McClelland, Zachary D. Dalebroux

Institutions: University of Oklahoma Health Sciences Center, University of California, Irvine

Language: English

Topic: Salmonella and Campylobacter epidemiology

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500

Funders: National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: G2532425450, Molecular Basis of Immunity, Barcoding a Salmonella gene knockout library, Mechanisms of PbgA involvement in Salmonella Typhimurium lipid homeostasis for bacterial pathogenesis, Molecular determinants of oxidative stress in Salmonella pathogenesis

OpenAlex ID: W4281785954

FWCI: 0.532

Cites: 76

Cited by: 6

Related to: 10