Work

Guidelines for reporting cell types: the MIRACL standard

Year: 2022

Type: preprint

Abstract: Cell types are at the root of modern biology, and describing them is a core task of the Human Cell Atlas project. Surprisingly, there are no standards for reporting new cell types, leading to a gap between classes mentioned in biomedical literature and the Cell Ontology, the primary registry of cell types. Here we introduce the Minimal Information Reporting About a CelL (MIRACL) standard, a guideline for describing cell types alongside scientific articles. In a MIRACL sheet, authors organize a label, a diagnostic description, a taxon, an anatomical structure, and a parent cell class for each cell type of interest. The MIRACL standard bridges the gap between wet-lab researchers and ontologists, facilitating the integration of biomedical knowledge into ontologies and artificial intelligence systems.

Source: arXiv (Cornell University)

DOI: 10.48550/arxiv.2204.09673

Authors: Lubiana, Tiago, Roncaglia, Paola, Mungall, Christopher J., Quardokus, Ellen M., Fortriede, Joshua D., Osumi-Sutherland, David, Diehl, Alexander D.

Institutions: Universidade de São Paulo, Ronin Institute, European Bioinformatics Institute, Lawrence Berkeley National Laboratory, Indiana University Bloomington, Indiana University, Cincinnati Children's Hospital Medical Center, University at Buffalo, State University of New York

Language: English

Topic: Biomedical Text Mining and Ontologies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Silicon Valley Community Foundation, European Bioinformatics Institute, Fundação de Amparo à Pesquisa do Estado de São Paulo, National Institutes of Health, National Heart, Lung, and Blood Institute

Awards: G527375157, Molecular Atlas of Lung Development Program (LungMAP) Phase 3 - Data Coordinating Center

OpenAlex ID: W4281893926

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Cited by: 1

Related to: 10