Work

Variation in the hemoglobin glycation index

Year: 2022

Type: review

Abstract: A high hemoglobin glycation index (HGI) has been repeatedly associated with greater risk for hypoglycemia in people with diabetes and greater risk for chronic vascular disease in people with or without diabetes. This review explores how different sources of analytical and biological variation in HbA1c and blood glucose individually and collectively affect the clinical information value of HGI. We conclude that HGI is a complex quantitative trait that is a clinically practical biomarker of risk for both hypoglycemia and chronic vascular disease.

Source: Journal of Diabetes and its Complications

DOI: 10.1016/j.jdiacomp.2022.108223

Authors: James M. Hempe, Daniel S. Hsia

Institutions: Louisiana State University Health Sciences Center New Orleans, Pennington Biomedical Research Center

Language: English

Topic: Advanced Glycation End Products research

Subfield: Clinical Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,100