Directing Multicellular Organization by Varying the Aspect Ratio of Soft Hydrogel Microwells (Adv. Sci. 17/2022)
Year: 2022
Type: article
Abstract: Directing Multicellular Organization In article number 2104649, Lewis H. Romer, David H. Gracias, and co-workers report the discovery of an endothelial cell self-organization mechanism that is guided simply by tuning the aspect ratio of 3D geometry on soft hydrogel substrates. This mechanism is driven by a balance between intra- and extracellular interactions and is independent of protein or chemical patterning.
Source: Advanced Science
Authors: Gayatri J. Pahapale, Jiaxiang Tao, Milos Nikolic, Sammy Gao, Giuliano Scarcelli, Sean X. Sun, Lewis H. Romer, David H. Gracias
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $5,200
OpenAlex ID: W4282595346