Work

Author response: Transcriptional regulation of cyclophilin D by BMP/Smad signaling and its role in osteogenic differentiation

Year: 2022

Type: peer-review

Abstract: Promoter studies identified BMP/Smad signaling as a transcriptional regulator of Ppif gene encoding cyclophilin D, a component of the mitochondrial permeability transition pore, and gain- and loss-of-function experiments determined how such regulation affects osteogenic differentiation.

DOI: 10.7554/elife.75023.sa2

Authors: Rubens Sautchuk, Brianna H Kalicharan, Katherine Escalera-Rivera, Jennifer H Jonason, George A Porter, Hani A Awad, Roman A Eliseev

Institutions: University of Rochester Medicine, University of Rochester

Language: English

Topic: Signaling Pathways in Disease

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4282829625

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