Work

Author response: Distinctive mechanisms of epilepsy-causing mutants discovered by measuring S4 movement in KCNQ2 channels

Year: 2022

Type: peer-review

Abstract: Because voltage-gated KCNQ2 channels are central to physiological and pathophysiological events, understanding how disease-causing mutations in different channel regions disrupt function will help future development of mutation-specific antiepileptic therapies.

DOI: 10.7554/elife.77030.sa2

Authors: Michaela A Edmond, Andy Hinojo-Perez, Xiaoan Wu, Marta E Perez Rodriguez, Rene Barro-Soria

Institution: University of Miami

Language: English

Topic: Ion channel regulation and function

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4282840587

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