Induction of Broadly Cross-Reactive Antibody Responses to SARS-CoV-2 Variants by S1 Nanoparticle Vaccines
Year: 2022
Type: article
Abstract: The emergence of SARS-CoV-2 variants led to an urgent demand for a broadly effective vaccine against the threat of variant infection. The spike protein S1-based nanoparticle designed in our study could elicit a comprehensive humoral response toward different SARS-CoV-2 variants of concern and variants of interest and will be helpful to combat COVID-19 globally.
Source: Journal of Virology
DOI: 10.1128/jvi.00383-22
Institutions: Sun Yat-sen University, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Provincial Center for Disease Control and Prevention, Southern University of Science and Technology, Xiamen University, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
Award: G1646818021
OpenAlex ID: W4282921572