Histamine/H1 receptor signaling in the parafacial region increases activity of chemosensitive neurons and respiratory activity in rats
Year: 2022
Type: article
Abstract: Histamine/H1 receptor signaling activates retrotrapezoid (RTN) neurons under control conditions and to a lesser extent in the presence of serotonin. These results suggest that RTN neurons have a limited capacity to respond to simultaneous activation of multiple Gq-coupled receptors.
Source: Journal of Neurophysiology
Institutions: University of Connecticut, Universidade de São Paulo
Language: English
Subfield: Endocrine and Autonomic Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
Funders: Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Ministério da Ciência, Tecnologia e Inovação, Conselho Nacional de Desenvolvimento Científico e Tecnológico, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Neurological Disorders and Stroke
Awards: Proposed roles of KCNQ2 Channels in Respiratory Homeostasis, G135236406, G1655383424, Roles of glycinergic neurons in Dravet syndrome-associated disordered breathing and mortality, G5120052177, G6168591780, G706045820, Glial chemosensitivity and control of breathing in Rett syndrome, G8122396338, G8361053648, Role of KCNQ2 Channels in Control of Breathing, G93856499
OpenAlex ID: W4282942923