Work

In situ microenvironment remodeling using a dual-responsive system: photodegradable hydrogels and gene activation by visible light

Year: 2022

Type: article

Abstract: microenvironment remodeling influenced stem cell proliferation and enlargement within the hydrogel. Furthermore, stem cells engineered to express light-activated VEGF and incorporated into the dual-responsive system were applied to wound healing and an ischemic hindlimb model, proving their potential application in regenerative medicine.

Source: Biomaterials Science

DOI: 10.1039/d2bm00617k

Authors: Eunjee A. Lee, Seoyeon Kim, Yoonhee Jin, Seung-Woo Cho, Kisuk Yang, Nathaniel S. Hwang, Hwan D. Kim

Institutions: Seoul National University, Yonsei University, Yonsei University Health System, Institute for Basic Science, Incheon National University, Korea National University of Transportation

Language: English

Topic: Hydrogels: synthesis, properties, applications

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Ministry of Education, Ministry of Health and Welfare, National Research Foundation of Korea, Ministry of Science and ICT, South Korea

Awards: G1600175797, G170728280, G4120097226, G4733762383, G6934853779

OpenAlex ID: W4283034885

FWCI: 0.461

Cites: 28

Cited by: 9

Related to: 10