Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for antiviral strategies
Year: 2022
Type: article
Source: Antiviral Research
Authors: Marwah Karim, Sirle Saul, Luca Ghita, Malaya Kumar Sahoo, Chengjin Ye, Nishank Bhalla, Chieh-Wen Lo, Jing Jin, Jun-Gyu Park, Belén Martinez-Gualda, Michael Patrick East, Gary L. Johnson, Benjamin A. Pinsky, Luis Martinez-Sobrido, Christopher R.M. Asquith, Aarthi Narayanan, Steven De Jonghe, Shirit Einav
Institutions: Stanford Medicine, Stanford University, Texas Biomedical Research Institute, George Mason University, Vitalant Research Institute, Rega Institute for Medical Research, KU Leuven, University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center, University of Eastern Finland, Chan Zuckerberg Biohub San Francisco
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: U.S. Department of Defense, Pharmaceutical Research and Manufacturers of America Foundation, National Institutes of Health, Defense Threat Reduction Agency, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, Congressionally Directed Medical Research Programs, Common Fund
Awards: G21146293, G2676286779, G3276391740, G3640120665, G4119534169, NAK Inhibitors for Combating Dengue, Ebola, COVID-19, and Other Emerging Viral Infections, Selective AAK1 and GAK Inhibitors for Combating Dengue and Other Emerging Viral Infections, Illuminating Function of the Understudied Druggable Kinome, G5850682332, G6047482813, G7147529592, NAK INHIBITORS FOR COMBATING DENGUE, EBOLA, COVID-19, AND OTHER EMERGING VIRAL INFECTIONS, G7618733506, SELECTIVE AAK1 AND GAK INHIBITORS FOR COMBATING DENGUE AND OTHER EMERGING VIRAL INFECTIONS, Advancing the development of a novel class of small molecules for treating pan-coronavirus infections, Applied Genomics in Infectious Diseases
OpenAlex ID: W4283216530