Mediators of the association between childhood BMI and educational attainment: analysis of a UK prospective cohort study
Year: 2022
Type: preprint
Abstract: Background Higher BMI in childhood is associated with lower academic achievement. Objective To explore potential pathways linking childhood BMI with educational attainment. Methods In the Avon Longitudinal Study of Parents and Children prospective cohort study (N=6234), we used structural equation models to assess the association between BMI z-scores at 11.7 years and educational attainment at 16 (General Certificate of Secondary Education (GCSE) results). Depressive symptoms, externalising symptoms, bullying, pressure to lose weight, and school enjoyment were considered as potential mediators. Results Higher BMI z-scores were associated with lower GCSE scores (total effect: females β = -3.20 95% CI -5.15, -1.26; males β = -2.98 95% CI -5.12, -0.84). Depressive symptoms and externalising symptoms partially mediated this association in females (indirect effect: β = -0.35 95% CI -0.63, -0.06, proportion mediated = 11%; β = -0.84 95% CI -1.77, 0.10, proportion mediated = 26%, respectively). In males, there was some evidence that the association was partially mediated by bullying (indirect effect β = -0.35 95% CI -0.74, 0.03, proportion mediated = 12%). Conclusions The association between childhood BMI and educational attainment may be partially mediated by depressive symptoms and externalising symptoms in females, and by bullying in males.
Source: medRxiv
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: G1192034430, G1605161196, G3233549029, G3345452146, Early-life stressors and LifeCycle health, G3831911591, G434337789, The Avon Longitudinal Study for Parents and Children: An international resource for population genomic and lifecourse epidemiology. Core programme support 2014-2019., G5562631338, Mediation analysis in life course epidemiology: methodological innovation and application to studies of obesity and cardiometabolic health
OpenAlex ID: W4283267059
