Work

Development of a Highly Efficient Long-Acting Cocaine Hydrolase Entity to Accelerate Cocaine Metabolism

Year: 2022

Type: article

Source: Bioconjugate Chemistry

DOI: 10.1021/acs.bioconjchem.2c00210

Authors: Fang Zheng, Zhenyu Jin, Jing Deng, Xiabin Chen, Xirong Zheng, Guojun Wang, Kyungbo Kim, Linyue Shang, Ziyuan Zhou, Chang-Guo Zhan

Institution: University of Kentucky

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Institute on Drug Abuse, Division of Chemistry

Awards: Development of Long-acting Cocaine Hydrolase as a Treatment for Cocaine Abuse, G3408010684, G5154985870, G5330388222, Development of a Cocaine-Metabolizing Enzyme for Drug Overdose Treatment, Development of a Long-acting Enzyme Therapy for Treatment of Cocaine Abuse, Validation of ghrelin hydrolysis as an effective approach to treatment of substance use disorders, Long-lasting cocaine-metabolizing enzyme for cocaine addiction treatment, Redesign of Butyrylcholinesterase for Cocaine Metabolism, Ghrelin Deacylase as a Treatment for Opioid Polysubstance Abuse, Development of Long-acting Cocaine Hydrolase as a Treatment for Cocaine Abuse

OpenAlex ID: W4283693941

FWCI: 1.143

Cites: 52

Cited by: 15

Related to: 10