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2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors

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Year: 2022
Type: article
Source: Bioorganic & Medicinal Chemistry
DOI: 10.1016/j.bmc.2022.116878
Authors: Dhananjayan Vasu, Huiying Li, Christine D. Hardy, Thomas L. Poulos, Richard B. Silverman
Institutions: Northwestern University, Chemistry of Life Processes Institute, University of California, Irvine
Language: English

Topic: Nitric Oxide and Endothelin Effects
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: Northwestern University, Ministry of Education, India, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences
Awards: G2748124137, G3893240564, Metalloenzyme structure, function, and as targets for neurodegeneration and bacterial pathogenesis, G9000059478, Cancer Center Support Grant
OpenAlex ID: W4283777932
FWCI: 2.149
Cites: 58
Cited by: 16
Related to: 10
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