Harmonizing PTSD severity scales across instruments and sites.
Year: 2022
Type: article
Abstract: OBJECTIVE: The variety of instruments used to assess posttraumatic stress disorder (PTSD) allows for flexibility, but also creates challenges for data synthesis. The objective of this work was to use a multisite mega analysis to derive quantitative recommendations for equating scores across measures of PTSD severity. METHOD: Empirical Bayes harmonization and linear models were used to describe and mitigate site and covariate effects. Quadratic models for converting scores across PTSD assessments were constructed using bootstrapping and tested on hold out data. RESULTS: ² = 0.985) with an average root mean squared error of 1.46 on sum scores. CONCLUSIONS: These methods allow PTSD symptom severity to be placed on multiple scales and offers interesting empirical perspectives on the role of harmonization in the behavioral sciences. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
Source: Neuropsychology
DOI: 10.1037/neu0000823
Authors: Eamonn Kennedy, Emily L. Dennis, Hannah M. Lindsey, Terri deRoon-Cassini, Stefan Du Plessis, Negar Fani, Milissa L. Kaufman, Nastassja Koen, Christine L. Larson, Sarah Laskowitz, Lauren A. M. Lebois, Rajendra A. Morey, Mary R. Newsome, Cori Palermo, Nicholas J. Pastorek, Abigail Powers, Randall Scheibel, Soraya Seedat, Antonia Seligowski, Dan J. Stein, Jennifer Stevens, Delin Sun, Paul Thompson, Maya Troyanskaya, Sanne J. H. van Rooij, Amanda A. Watts, Carissa W. Tomas, Wright Williams, Frank G. Hillary, Mary Jo Pugh, Elisabeth A. Wilde, David F. Tate
Institutions: University of Utah, Medical College of Wisconsin, University of Cape Town, Emory University, Harvard University, University of Wisconsin–Milwaukee, Duke University, Baylor College of Medicine, Stellenbosch University, University of Southern California, Michael E. DeBakey VA Medical Center, Penn State Milton S. Hershey Medical Center
Language: English
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: hybrid
Funders: U.S. Department of Veterans Affairs, National Institutes of Health, National Institute on Aging, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke, National Institute of Biomedical Imaging and Bioengineering, National Center for Research Resources, National Center for Advancing Translational Sciences, National Center for Complementary and Integrative Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: G1394456878, G1890943264, G2022553733, G205869997, Neurobiology of Traumatic Dissociation in a Transdiagnostic Study of Women with Childhood Maltreatment, G2500699706, G344804108, G3840218660, G4326722283, G4440719393, G4661676191, G483946173, G490900884, G4962453174, G5644117679, G567439960, ENIGMA Center for Worldwide Medicine, Imaging & Genomics, G661928818, G700495459, G888994554, G9000333532, A Multi-Modal Investigation of Neurophysiological Deficits in PTSD
OpenAlex ID: W4284881956