Work

Increased FOXA1 levels induce apoptosis and inhibit proliferation in FOXA1-low expressing basal breast cancer cells.

Year: 2022

Type: article

Abstract: . Our cumulative results suggest that FOXA1 suppresses the basal breast cancer cells with FOXA1-low expressing status independent of ESR1 by inducing apoptosis and inhibiting cell proliferation, thereby implicating its potential therapeutic role in this group of breast cancer.

Source: PubMed Central

Authors: Ke Xia, Wenqiang Huang, Xiaoyun Zhao, Xiaoqin Huang, Yan Chen, Li Yu, Yongjun Tan

Institution: Hunan University

Language: English

Topic: Breast Cancer Treatment Studies

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4285048689

FWCI: 0.625

Cites: 55

Cited by: 7

Related to: 10