Work

Fibrolamellar Carcinoma

Year: 2021

Type: article

Abstract: Fibrolamellar carcinoma (FL-Ca) is a primary malignant liver tumor at unknown etiology, without cirrhosis and usually without an increase at tumor markers, which occurs mainly in young patients. As it can simulate malignant and benign tumors, particularly FNH, diagnosis is difficult. Ultrasound and angiography show mostly uncharacteristic features. The highest specificity has CT, if calcifications are present, because these calcifications in a tumor similar to FNH are pathognomonic for FL-Ca. In MRI the central scars of FL-Ca and FNH have a different signal intensity in T2-weighted images, so that MRI becomes more and more important in the differential diagnosis to FNH.

Source: Applied Radiology

DOI: 10.37549/ar2716

Authors: Luz Adriana Escobar, Julian Kirchner, Soleen Ghafoor, Olca Basturk, Richard K Do

Institutions: Memorial Sloan Kettering Cancer Center, Heinrich Heine University Düsseldorf

Language: German

Topic: Hepatocellular Carcinoma Treatment and Prognosis

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: National Cancer Institute