Work

Cholangiocarcinoma: The Present and Future of Targeted Therapies

Year: 2022

Type: article

Abstract: Cholangiocarcinomas (CCAs) are a heterogenous group of cancers arising from the biliary epithelium. CCAs tend to metastasize with early lymph node involvement lending to poor surgical outcomes and need for systemic therapy. Given the paucity of successful therapies in these cancers, it is important to understand the molecular drivers and to develop therapeutic strategies using targeted therapies either alone or in combination. The molecular landscape offers several new potentially targetable drivers.

Source: touchREVIEWS in Oncology & Haematology

DOI: 10.17925/ohr.2022.18.1.9

Authors: Aparna Kalyan, Rachna T Shroff

Institutions: Robert H. Lurie Comprehensive Cancer Center of Northwestern University, University of Arizona Cancer Center

Language: English

Topic: Cholangiocarcinoma and Gallbladder Cancer Studies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4285612570