The impact of spleen volume on the survival of metastatic pancreatic adenocarcinoma patients receiving nanoliposomal irinotecan.
Year: 2022
Type: article
Abstract: , prior fluoropyrimidine use, liver metastasis, and low-dose subgroup were independent poor prognostic factors. A low average nal-IRI dose was significantly associated with poor prognosis, especially among patients with splenomegaly. Further pharmacological studies should validate the relevance of spleen volume on the treatment outcomes of nal-IRI.
Source: PubMed
Institutions: National Taiwan University, National Taiwan University Hospital, National Yang Ming Chiao Tung University, National Health Research Institutes, Taipei Veterans General Hospital, PharmaEngine, Inc. (Taiwan), Chang Gung University, Linkou Chang Gung Memorial Hospital, China Medical University, China Medical University Hospital, National Cheng Kung University Hospital, National Cheng Kung University, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung Medical University Chung-Ho Memorial Hospital, Chung Shan Medical University Hospital, Tri-Service General Hospital
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4285741446