Work

A novel score system for predicting conversion to no evidence of Disease (C-NED) in initially unresectable colorectal cancer liver metastases.

Year: 2022

Type: article

Abstract: < 0.001). The C-indexes of the C-NED score for predicting successful conversion outcome in the internal cohort and external cohort were 0.734 (95% confidence interval (CI), 0.668-0.800) and 0.736 (95% CIs, 0.566-0.907), respectively. Median progression-free survival (PFS) time (P = 0.001) and overall survival (OS) time (P = 0.003) were statistically significant different among different C-NED score groups. Our study demonstrated that the C-NED score is an effective scoring system that indicates the actual conversion probability for initially unresectable CRLM patients before treatment, which can serve as a tool that guides optimal first-line management strategies.

Source: PubMed

Authors: Weihao Li, Jian Zhou, Tianqi Zhang, Yi Tai, Yanbo Xu, Yanfang Bai, Yu Jiang, Zhenhai Lu, Liren Li, Jinhua Huang, Zhizhong Pan, Xiaojun Wu, Jianhong Peng, Junzhong Lin

Institutions: State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center

Language: English

Topic: Colorectal Cancer Treatments and Studies

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4286829621

FWCI: 0.112

Cites: 37

Cited by: 1

Related to: 10