Targeting AML dependency on VCP-mediated DNA repair through a selective second-generation small molecule inhibitor
Year: 2021
Type: article
Abstract: International audience
Authors: Roux, Blandine, Vaganay, Camille, Vargas, Jesse, D, Alexe, Gabriela, Benaksas, Chaima, Pardieu, Bryann, Fenouille, Nina, Ellegast, Jana, M, Malolepsza, Edyta, Ling, Frank, Sodaro, Gaetano, Ross, Linda, Pikman, Yana, Conway, Amy, S, Tang, Yangzhong, Wu, Tony, Anderson, Daniel, J, Le Moigne, Ronan, Zhou, Han-Jie, Luciano, Frédéric, Hartigan, Christina, R, Galinsky, Ilene, Deangelo, Daniel, J, Stone, Richard, M, Auberger, Patrick, Schenone, Monica, Carr, Steven, A, Guirouilh-Barbat, Josée, Lopez, Bernard, Khaled, Mehdi, Lage, Kasper, Hermine, Olivier, Hemann, Michael, T, Puissant, Alexandre, Stegmaier, Kimberly, Benajiba, Lina
Institutions: Génomes, biologie cellulaire et thérapeutiques, Hôpital Saint-Louis, Broad Institute, Boston Children's Hospital, Harvard University, Dana-Farber Cancer Institute, Hôpital l'Archet, Centre Méditerranéen de Médecine Moléculaire, Institut Cochin, Immunologie intégrative des tumeurs et immunothérapie du cancer, Inserm, Institut des Maladies Génétiques Imagine, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: National Science Foundation, Leukemia and Lymphoma Society, Gilead Sciences, Philippe Foundation, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Gilead Research Scholars, Institut National de la Santé et de la Recherche Médicale, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Fondation Bettencourt Schueller, Fondation Schlumberger pour l’Education et la Recherche, National Institutes of Health, National Cancer Institute
OpenAlex ID: W4286860162