Work

Cilostazol eliminates radiation-resistant glioblastoma by re-evoking big conductance calcium-activated potassium channel activity.

Year: 2021

Type: article

Abstract: growth and prolonged survival. As such, inactivation of the BK channel assists GBM in developing radiation resistance. Accordingly, restoring BK channel activity may be an effective strategy to improve therapeutic efficacy, and cilostazol could be repurposed to treat GBM.

Source: PubMed Central

Authors: Chan-Chuan Liu, Cheng-Lin Wu, I-Chun Yeh, Sheng-Nan Wu, Chun-I Sze, Po-Wu Gean

Institutions: National Cheng Kung University Hospital, Kuo General Hospital, National Cheng Kung University

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4287544613

FWCI: 0.61

Cites: 60

Cited by: 7

Related to: 10