Work

Omics Lethal Human Viruses, Ebola Experiment EU937001

Year: 2021

Type: article

Abstract: The purpose of this experiment was to evaluate the human host response to Zaire Ebola wild-type virus and mutant virus infection. Samples were obtained from human histiocytic lymphoma cells (U937), expressing the Ebola VP30 protein, infected with wild-type Zaire Ebola (in ΔVP30 background) and Δmucin mutant virus encoding a glycoprotein lacking the mucin domain for mRNA and miRNA transcriptome expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset downloads have a direct relationship to a primary sample submission corresponding to a specific Ebola virus infection.

Source: OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)

DOI: 10.25584/lhveu937001/1661911

Authors: Anderson, Lindsey, Eisfeld, Amie, Waters, Katrina

Institutions: Pacific Northwest National Laboratory, University of Wisconsin–Madison

Language: English

Topic: Viral Infections and Outbreaks Research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4287663717

FWCI: 0.159

Cites:

Cited by: 2

Related to: 10