Year: 2020
Type: article
Abstract: Needle-free injector technology (NFIT) has drawn attention due to their advantages. By using NFIT, it can be used several times unlike a conventional needle. Also, it makes patients free from pain. Since NFIT by jet injection is achieved by ejecting a liquid drug through a narrow orifice at high pressure, thereby creating a fine high-speed fluid jet that can readily penetrate skin and tissue. Until very recently, all jet injectors utilized force-and pressure-generating principles that progress injection in an uncontrolled manner with limited ability to regulate delivery volume and injection depth. In order to address these shortcomings, we have developed a controllable jet injection device, based on a custom high-stroke linear Lorentz-force motor. Using this device, we can monitor and modulate continuously the speed of the drug jet and regulate precisely the volume of drug delivered during the injection process.
Author: Eun-Sung Jekal
Institution: ETH Zurich
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W3008381549