Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
Year: 2020
Type: article
Source: Nature
Authors: Julia Bergild McBrien, Maud Mavigner, Lavinia Franchitti, S. Abigail Smith, Erick White, Gregory K. Tharp, Hasse Walum, Kathleen Busman-Sahay, Christian R. Aguilera-Sandoval, William O. Thayer, Rae Ann Spagnuolo, Martina Kovarova, Angela Wahl, Barbara Cervasi, David M. Margolis, Thomas H. Vanderford, Diane G. Carnathan, Mirko Paiardini, Jeffrey D. Lifson, John H. Lee, Jeffrey T. Safrit, Steven E. Bosinger, Jacob D. Estes, Cynthia A. Derdeyn, J. Victor Garcia, Deanna A. Kulpa, Ann Chahroudi, Guido Silvestri
Institutions: Emory University, Emory National Primate Research Center, Oregon Health & Science University, Vaccine and Gene Therapy Institute, University of North Carolina at Chapel Hill, Frederick National Laboratory for Cancer Research, ImmunityBio (United States), Oregon National Primate Research Center
Language: English
Topic: HIV Research and Treatment
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
Awards: Slide Scanner for the ONPRC Imaging and Morphology Core, Role of Myeloid Cells in HIV latency in the Periphery and the CNS, Plug & Purge: In Vivo Targeting of Active HIV Reservoirs That Persist Despite ART, Collaboratory of AIDS Researchers for Eradication (CARE), G386607036, Mechanisms of SIV suppression by CD8+ lymphocytes, G4689185066, The Role of Human Gut Microbiota in HIV-1 Rectal Acquisition, Replication, and Pathogenesis, G5888954722, B and T Cell Biology of Protection from and Eradication of SIV/SHIV Infection, Illumina NovaSeq 6000 High Throughput DNA Sequencer for Emory University, CD8 T cell suppression of HIV latency establishment and maintenance in virally suppressed individuals, Antiviral role of CD8+T cells in ART-treated SIV-infected macaques, Maintenance of the SPF Breeding Colonies at Yerkes National Primate Research Center, Center for AIDS Research at Emory University, Support for National Primate Research Center, Emory National Primate Research Center
OpenAlex ID: W3001801234