Work

Vertigo‐Associated Vomiting

Year: 2022

Type: article

Abstract: Thiamine deficiency can manifest as Wernicke encephalopathy, with the classic clinical triad of altered mental status, nystagmus, and ataxia. Although a rare diagnosis in pediatric patients within developed countries, gastrointestinal disorders that impair nutritional intake and absorption can place patients at higher risk. Rapid diagnosis and early empiric treatment of Wernicke encephalopathy is paramount due to high risk of mortality and long-term morbidity. We present a patient with intestinal failure who developed thiamine deficiency following weaning off parenteral nutrition with acute onset of vertigo-associated vomiting. In the absence of consensus guidelines for treatment dosing and duration, in both adult and pediatric populations, we review prior pediatric cases and propose a strategy for dosing with symptom-guided step-up approach to maximize treatment efficacy in a time-conscious manner.

Source: JPGN Reports

DOI: 10.1097/pg9.0000000000000226

Authors: Xiaoyi Zhang, Vincent Arnone, Kimberly Ackerman, Feras Al‐issa

Institutions: Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, West Virginia University

Language: English

Topic: Alcoholism and Thiamine Deficiency

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $1,900