Work

Systemic induction of senescence in young mice after single heterochronic blood exchange

Year: 2022

Type: article

Source: Nature Metabolism

DOI: 10.1038/s42255-022-00609-6

Authors: Ok Hee Jeon, Melod Mehdipour, Tae-Hwan Gil, Minha Kang, Nicholas W. Aguirre, Zachery R. Robinson, Cameron Kato, Jessy Etienne, Hyo Gyeong Lee, Fatouma Alimirah, Vighnesh Walavalkar, Pierre-Yves Desprez, Michael J. Conboy, Judith Campisi, Irina M. Conboy

Institutions: Buck Institute for Research on Aging, Korea University, QB3, University of California, Berkeley, University of California, San Francisco, Lawrence Berkeley National Laboratory

Language: English

Topic: Telomeres, Telomerase, and Senescence

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, Glenn Foundation for Medical Research, Korea University, National Research Foundation of Korea, National Institutes of Health, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute of Biomedical Imaging and Bioengineering

Awards: Defined pharmacology for multi-tissue rejuvenation acting through youthful normalization of p16, New Generation Blood Exchange Devices for Enhancing Tissue Regeneration and Health, Treatment of Duchenne Muscular Dystrophy with Cas9 Protein Complexed to Gold Nanoparticles, G3133880777, G3183218242, G3394488700, Cellular senescence as a mediator of mitochondrial dysfunction-induced aging, G3741393083, Senescent cells as a source of pro-geronic factors, G42092873, G4345238707, G4805783754, G5109492772, G5649398216, G5917295334, G6941925097, DNA Repair, Mutations and Cellular Aging, G8343260726, Identifying signatures of brain aging through heterochronic blood exchange

OpenAlex ID: W4288427183

FWCI: 14.23

Cites: 45

Cited by: 114

Related to: 10