Work

Predicting COPD Progression in Current and Former Smokers Using a Joint Model for Forced Expiratory Volume in 1 Second and Forced Expiratory Volume in 1 Second to Forced Vital Capacity Ratio

Year: 2022

Type: article

Study design: Observational Study

Abstract: /FVC of at least 5% tended to have more emphysema, higher functional residual capacity, higher airway wall thickness as measured by Pi10, lower FVC to total lung capacity ratio and a lower body mass index at baseline, all relative to overall cohort averages. The model developed can be used to predict progression for any potential COPD individual, based on demographic, symptom, computed tomography, and comorbidity variables.

Source: Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation

DOI: 10.15326/jcopdf.2022.0281

Authors: Matthew Strand, Aastha Khatiwada, David Baraghoshi, David Lynch, Edwin K. Silverman, Surya P. Bhatt, Erin Austin, Elizabeth A. Regan, Aladin M. Boriek, James D. Crapo

Institutions: National Jewish Health, Brigham and Women's Hospital, Harvard University, University of Alabama at Birmingham, UAB Medicine, University of Colorado Denver, Baylor College of Medicine

Language: English

Topic: Chronic Obstructive Pulmonary Disease (COPD) Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Pfizer, AstraZeneca, GlaxoSmithKline, COPD Foundation, Sunovion, Genentech, National Heart, Lung, and Blood Institute

Awards: G5258357286, (2 of 2) Genetic Epidemiology of COPD, (1 of 2) Genetic Epidemiology of COPD, G820522361, G8354759825, G8643874822, G8819318481

OpenAlex ID: W4288774601

FWCI: 0.806

Cites: 22

Cited by: 5

Related to: 10