Work

Site-Selective Electrochemical Oxidation of Glycosides

Year: 2023

Type: article

Abstract: Quinuclidine-mediated electrochemical oxidation of glycopyranosides provides C3-ketosaccharides with high selectivity and good yields. The method is a versatile alternative to Pd-catalyzed or photochemical oxidation and is complementary to the 2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPO)-mediated C6-selective oxidation. Contrary to the electrochemical oxidation of methylene and methine groups, the reaction proceeds without oxygen.

Source: ACS Catalysis

DOI: 10.1021/acscatal.2c06318

Authors: Marios Kidonakis, Augustin Villotet, Martin D. Witte, Sebastian B. Beil, Adriaan J. Minnaard

Institution: University of Groningen

Language: English

Topic: Carbohydrate Chemistry and Synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $5,000

Funders: Rijksuniversiteit Groningen, Ministerie van Economische Zaken, Nederlandse Organisatie voor Wetenschappelijk Onderzoek