Work

The Integrative Conjugative Element ICESpyM92 Contributes to Pathogenicity of Emergent Antimicrobial-Resistant emm92 Group A Streptococcus

Year: 2022

Type: article

Abstract: DGE indicates ICESpyM92 influences GAS global gene expression in a background-dependent manner. Our study links virulence and AMR on a unique MGE via MGE-related DGE and highlights the importance of investigating associations between AMR-encoding MGEs and pathogenicity.

Source: Infection and Immunity

DOI: 10.1128/iai.00080-22

Authors: Luis Alberto Vega, Misu A. Sanson, María Belén Cubria, Shrijana Regmi, Brittany J. Shah, Samuel A. Shelburne, Anthony R. Flores

Institutions: The University of Texas Health Science Center at Houston, The University of Texas MD Anderson Cancer Center

Language: English

Topic: Streptococcal Infections and Treatments

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases

Awards: Texas Medical Center Training Program in Antimicrobial Resistance, Impact of a novel emm-enn gene fusion event on epidemic behavior of group A streptococcus, G6861867245

OpenAlex ID: W4289316010

FWCI: 1.106

Cites: 36

Cited by: 7

Related to: 10