Work

A positron emission tomography imaging probe selectively targeting the BD1 bromodomain and extra-terminal domain

Year: 2022

Type: article

Abstract: C]1a demonstrated translational potential in the non-human primate (NHP) PET imaging study, which sets the stage for clinical translation.

Source: Chemical Communications

DOI: 10.1039/d2cc03785h

Authors: Ping Bai, Liu Yan, Frederick A. Bagdasarian, Moses Q. Wilks, Hsiao-Ying Wey, Changning Wang

Institutions: Harvard University, Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, Gordon Center for Medical Imaging

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute on Aging, National Institute on Drug Abuse

Awards: Selective PET imaging probes targeting BD1 of N-terminal bromodomains, Gut Microbiota Underlies the Heterogeneity of Aging Brain's Susceptibility to Postoperative Delirium, Program to enrich translation and multimodal research in Alzheimers disease and related dementias, Massachusetts Alzheimer's Disease Research Center (MADRC)

OpenAlex ID: W4289450723

FWCI: 0.653

Cites: 23

Cited by: 11

Related to: 10