Polygenic risk score analysis identifies deleterious protein-coding variants in novel immune pathway genes ATP8B4, FCGR1A, and LILRB1 that associate with Alzheimer’s disease.
Year: 2022
Type: preprint
Source: Research Square
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: Michael J. Fox Foundation for Parkinson's Research, Arizona Department of Health Services, Arizona Biomedical Research Commission, National Institutes of Health, National Institute on Aging, National Heart, Lung, and Blood Institute, National Human Genome Research Institute, National Institute of Neurological Disorders and Stroke
Awards: G1052080286, Genomic approach to identification of microglial networks involved in Alzheimer disease risk, G1194337659, G1299646910, G1307745024, G1315589061, G1379949353, G1606131442, G1783502158, G1871439151, G2161113364, G250893170, G2682171662, G2898431357, G2908616768, G3002044485, G305289672, G3228411741, G3250808129, G3521153818, G3540482749, G3687506083, ADSP Follow-up in Multi-Ethnic Cohorts via Endophenotypes, Omics & Model Systems, G415358893, G418866124, G4365567135, Replication and Extension of ADSP Discoveries in African-Americans, G4702044304, G4727311221, G4728428359, G4791902628, G5056103449, Alzheimer's Disease Genetics Consortium, G5558075022, G5681130674, G5752060496, Additional Sequencing Cohorts for the Alzheimer's Disease Sequencing Project, G6030318873, Consortium for Alzheimers Sequence Analysis (CASA), G6125194395, G6648385527, G695448792, Arizona Alzheimer's Disease Core Center, G7161884846, G7369527170, G7431531211, G7457767463, G7628628223, National Brain and Tissue Resource for Parkinson's Disease and Related Disorders, G7747731141, Genomic Characterization of Alzheimer's Disease Risk in the Puerto Rican Population, G7887587830, G7924111682, G8011407006, G824429988, G837617365, G8508790466, Identification and characterization of AD risk networks using multi-dimensional "omics" data, G9000004484, G9000009691, G9000019776, G9000025708, G9000038551, G9000038879, G9000044681, G9000101681, G9000106852, G9000114517, G9000126758, G9000128249, G9000130884, G9000159448, G9000205406, G9000252960, G961669115
OpenAlex ID: W4289654108