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A Flexible Joint Longitudinal-Survival Model for Analysis of End-Stage\n Renal Disease Data

Year: 2018
Type: article
Abstract: We propose a flexible joint longitudinal-survival framework to examine the\nassociation between longitudinally collected biomarkers and a time-to-event\nendpoint. More specifically, we use our method for analyzing the survival\noutcome of end-stage renal disease patients with time-varying serum albumin\nmeasurements. Our proposed method is robust to common parametric assumptions in\nthat it avoids explicit distributional assumptions on longitudinal measures and\nallows for subject-specific baseline hazard in the survival component. Fully\njoint estimation is performed to account for the uncertainty in the estimated\nlongitudinal biomarkers included in the survival model.
Language: English
Open Access status: green
OpenAlex ID: W4289763397
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