Work

Mitochondria-targeted alginate/triphenylphosphonium-grafted-chitosan for treatment of hepatocellular carcinoma

Year: 2022

Type: article

Abstract: studies demonstrated an enhanced antitumor bioactivity for the mitotropic NPs along with a reduced biological toxicity profile. In conclusion, this study proposes a promising nanocarrier system for the efficient targeting of DOX to the mitochondria of hepatic tumors.

Source: RSC Advances

DOI: 10.1039/d2ra03240f

Authors: Kholoud K. Arafa, Mohamed A. Hamzawy, Shaker A. Mousa, Ibrahim M. El-Sherbiny

Institutions: Zewail City of Science and Technology, Fayoum University, Albany College of Pharmacy and Health Sciences

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042