Year: 2022
Type: editorial
Abstract: Editorial on the Research Topic Nanomaterials for targeted delivery of therapeutic and imaging agents Nanomedicine has been a growing field over the last couple of decades, and the development of new platforms for improving disease diagnosis, therapies, and drug formulations has been constantly evolving.The rapid clinical translation of the current Covid-19 mRNA vaccines is also in part due to the application of nanotechnology mediated gene delivery.Nanomaterials, while helping to develop targeted delivery of therapeutics, also serve as imaging agents/contrasts for monitoring the disease status in vivo using various imaging modalities.Nano-agents like gold nanoparticles, nanodiamonds, and carbon nanotubes work as excellent drug carriers while helping in intracellular tracking of delivered agents.To highlight the application of nanomaterials in therapy and diagnostic imaging (theragnostic), we invited articles related to this topic from established investigators.We received a total of seven manuscripts, including four original research manuscripts and three review articles, among of which six of them that were related to nanomaterials in theranostic applications were accepted and assembled as a special issue.As shown in the figure (Figure 1), the original research manuscript by De Canha et al. highlighted the preparation of gold nanoparticles by incorporating extract of Helichrysum odoratissimum as a potential nanoformulation for effective inhibition of Cutibacterium acnes, a commensal that causes acne in human skin, adhesion without showing any antibacterial activity (De Canha et al.).This serves as a useful formulation for preventing bacterial disease, and at the same time overcomes the possibility of developing a drug resistant bacterium, a common problem associated with the use of antibiotics for treating bacterial diseases.Similarly, Naqvi et al., has developed a polyethyleneimine (PEI) stabilized human serum albumin (HSA) nanoparticles for simultaneous delivery of a small molecule antioxidant sulforaphane (SF) and an antioxidant responsive SOD1 gene for improving the
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,950
OpenAlex ID: W4290080006