Work

Lack of full sequencing GBA1 studies for patients with Parkinson’s disease in Latin America

Year: 2022

Type: article

Study designs: Systematic Review, Meta-Analysis

Abstract: Full sequencing of the GBA1 gene in patients with Parkinson's disease provides a wide screening of pathogenic variants, but less developed regions of the world, like Latin America, may have difficulties in performing full sequencing. We performed a systematic review with meta-analysis to explore the prevalence and the odds ratio of specific GBA1 variants in Parkinson's disease in Latin America. We noted a lack of full sequencing GBA1 studies in Latin America.

Source: npj Parkinson s Disease

DOI: 10.1038/s41531-022-00358-z

Authors: Bruno Lopes Santos-Lobato, Artur F. Schumacher-Schuh, Ignacio F. Mata

Institutions: Universidade Federal do Pará, Hospital de Clínicas de Porto Alegre, Cleveland Clinic, Cleveland Clinic Research

Language: English

Topic: Lysosomal Storage Disorders Research

Subfield: Physiology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,190